Viral RNA Degradation and Diffusion Act as a Bottleneck for the Influenza A Virus Infection Efficiency

After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to release of the viral segmented genome destined to r...

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Detalles Bibliográficos
Autores principales: Schelker, Max, Mair, Caroline Maria, Jolmes, Fabian, Welke, Robert-William, Klipp, Edda, Herrmann, Andreas, Flöttmann, Max, Sieben, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079570/
https://www.ncbi.nlm.nih.gov/pubmed/27780209
http://dx.doi.org/10.1371/journal.pcbi.1005075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079570/
https://www.ncbi.nlm.nih.gov/pubmed/27780209
http://dx.doi.org/10.1371/journal.pcbi.1005075

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