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A Single Amino Acid Dictates Protein Kinase R Susceptibility to Unrelated Viral Antagonists

During millions of years of coevolution with their hosts, cytomegaloviruses (CMVs) have succeeded in adapting to overcome host-specific immune defenses, including the protein kinase R (PKR) pathway. Consequently, these adaptations may also contribute to the inability of CMVs to cross species barrier...

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Detalles Bibliográficos
Autores principales: Carpentier, Kathryn S., Esparo, Nicolle M., Child, Stephanie J., Geballe, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079575/
https://www.ncbi.nlm.nih.gov/pubmed/27780231
http://dx.doi.org/10.1371/journal.ppat.1005966