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Engineering Permissive Insertion Sites in the Bacteriophage Phi29 DNA-Linked Terminal Protein

Many different DNA delivery vehicles have been developed and tested, all with their advantages and disadvantages. The bacteriophage phi29 terminal protein (TP) is covalently linked to the 5’ ends of the phage genome during the DNA replication process. Our approach is to utilize this TP as a platform...

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Detalles Bibliográficos
Autores principales: Gella, Pablo, Salas, Margarita, Mencía, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079584/
https://www.ncbi.nlm.nih.gov/pubmed/27780219
http://dx.doi.org/10.1371/journal.pone.0164901