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Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

Activation of the sympathetic nervous system (SNS) constitutes a putative mechanism of obesity-induced insulin resistance. Thus, we hypothesized that inhibiting the SNS by using renal denervation (RDN) will improve insulin sensitivity (S(I)) in a nonhypertensive obese canine model. S(I) was measured...

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Detalles Bibliográficos
Autores principales: Iyer, Malini S., Bergman, Richard N., Korman, Jeremy E., Woolcott, Orison O., Kabir, Morvarid, Victor, Ronald G., Clegg, Deborah J., Kolka, Cathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079632/
https://www.ncbi.nlm.nih.gov/pubmed/27495220
http://dx.doi.org/10.2337/db16-0698