Cargando…

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

Activation of the sympathetic nervous system (SNS) constitutes a putative mechanism of obesity-induced insulin resistance. Thus, we hypothesized that inhibiting the SNS by using renal denervation (RDN) will improve insulin sensitivity (S(I)) in a nonhypertensive obese canine model. S(I) was measured...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iyer, Malini S., Bergman, Richard N., Korman, Jeremy E., Woolcott, Orison O., Kabir, Morvarid, Victor, Ronald G., Clegg, Deborah J., Kolka, Cathryn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079632/ https://www.ncbi.nlm.nih.gov/pubmed/27495220 http://dx.doi.org/10.2337/db16-0698

Ejemplares similares

Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin
por: Asare-Bediako, Isaac, et al.
Publicado: (2018)

Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets
por: Woolcott, Orison O., et al.
Publicado: (2015)

A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided
por: Paszkiewicz, Rebecca L., et al.
Publicado: (2020)

Correction: Paszkiewicz et al. A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting That Central Effects Can Be Avoided. Int. J. Mol. Sci. 2020, 21, 6639
por: Paszkiewicz, Rebecca L., et al.
Publicado: (2021)

Increase in visceral fat per se does not induce insulin resistance in the canine model
por: Castro, Ana V.B., et al.
Publicado: (2014)

Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes
por: Ionut, Viorica, et al.
Publicado: (2016)

Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance
por: Zhang, Wei, et al.
Publicado: (2016)

Failure of Homeostatic Model Assessment of Insulin Resistance to Detect Marked Diet-Induced Insulin Resistance in Dogs
por: Ader, Marilyn, et al.
Publicado: (2014)

Insulin access to skeletal muscle is preserved in obesity induced by polyunsaturated diet
por: Broussard, Josiane L., et al.
Publicado: (2017)

Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes. Diabetes 2019;68:1709–1716
por: Bergman, Richard N., et al.
Publicado: (2019)

Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet
por: Becker, Melanie, et al.
Publicado: (2010)

High-Fat Diet-Induced Insulin Resistance Does Not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets
por: Woolcott, Orison O., et al.
Publicado: (2015)

Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy
por: Eller, Kathrin, et al.
Publicado: (2011)

Relative Fat Mass as an estimator of whole-body fat percentage among children and adolescents: A cross-sectional study using NHANES
por: Woolcott, Orison O., et al.
Publicado: (2019)

Relative fat mass (RFM) as a new estimator of whole-body fat percentage ─ A cross-sectional study in American adult individuals
por: Woolcott, Orison O., et al.
Publicado: (2018)

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance
por: Elias, Ivet, et al.
Publicado: (2012)

Loss of ACE2 Exaggerates High-Calorie Diet–Induced Insulin Resistance by Reduction of GLUT4 in Mice
por: Takeda, Masao, et al.
Publicado: (2013)

Lipoprotein Subfraction Cholesterol Distribution Is Proatherogenic in Women With Type 1 Diabetes and Insulin Resistance
por: Maahs, David M., et al.
Publicado: (2010)

A High-Fat Diet Attenuates AMPK α1 in Adipocytes to Induce Exosome Shedding and Nonalcoholic Fatty Liver Development In Vivo
por: Yan, Chenghui, et al.
Publicado: (2021)

Developmental Programming by Maternal Insulin Resistance: Hyperinsulinemia, Glucose Intolerance, and Dysregulated Lipid Metabolism in Male Offspring of Insulin-Resistant Mice
por: Isganaitis, Elvira, et al.
Publicado: (2014)

IGF-I Bioactivity in an Elderly Population: Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome
por: Brugts, Michael P., et al.
Publicado: (2010)

Glucagon-Like Peptide 1 Recruits Muscle Microvasculature and Improves Insulin’s Metabolic Action in the Presence of Insulin Resistance
por: Chai, Weidong, et al.
Publicado: (2014)

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium
por: Abbas, Afroze, et al.
Publicado: (2011)

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice
por: Tanigaki, Keiji, et al.
Publicado: (2016)

CD14 Modulates Inflammation-Driven Insulin Resistance
por: Fernández-Real, José Manuel, et al.
Publicado: (2011)

Effect of Endothelium-Specific Insulin Resistance on Endothelial Function In Vivo
por: Duncan, Edward R., et al.
Publicado: (2008)

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
por: Jelenik, Tomas, et al.
Publicado: (2017)

Increased Lipolysis, Diminished Adipose Tissue Insulin Sensitivity, and Impaired β-Cell Function Relative to Adipose Tissue Insulin Sensitivity in Obese Youth With Impaired Glucose Tolerance
por: Kim, Joon Young, et al.
Publicado: (2017)

Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
por: Huang-Doran, Isabel, et al.
Publicado: (2011)

Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans
por: Badin, Pierre-Marie, et al.
Publicado: (2011)

Effects of Rosiglitazone, Glyburide, and Metformin on β-Cell Function and Insulin Sensitivity in ADOPT
por: Kahn, Steven E., et al.
Publicado: (2011)

Angiotensin II Receptors Modulate Muscle Microvascular and Metabolic Responses to Insulin In Vivo
por: Chai, Weidong, et al.
Publicado: (2011)

Brain Insulin Action Regulates Hypothalamic Glucose Sensing and the Counterregulatory Response to Hypoglycemia
por: Diggs-Andrews, Kelly A., et al.
Publicado: (2010)

Adaptation of β-Cell and Endothelial Function to Carbohydrate Loading: Influence of Insulin Resistance
por: Hurwitz, Barry E., et al.
Publicado: (2015)

Variable Hepatic Insulin Clearance with Attendant Insulinemia is the Primary Determinant of Insulin Sensitivity in the Normal Dog
por: Ader, Marilyn, et al.
Publicado: (2013)

Age-Related Impairment in Insulin Release: The Essential Role of β(2)-Adrenergic Receptor
por: Santulli, Gaetano, et al.
Publicado: (2012)

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?
por: Amati, Francesca, et al.
Publicado: (2011)

Loss of Inverse Relationship Between Pulsatile Insulin and Glucagon Secretion in Patients With Type 2 Diabetes
por: Menge, Björn A., et al.
Publicado: (2011)

Perivascular Adipose Tissue Control of Insulin-Induced Vasoreactivity in Muscle Is Impaired in db/db Mice
por: Meijer, Rick I., et al.
Publicado: (2013)

Circulating Retinol-Binding Protein-4 Concentration Might Reflect Insulin Resistance–Associated Iron Overload
por: Fernández-Real, José Manuel, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_j9u59oc058kkcpr8nu5cudk18h