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Enhanced Integrin α4β1–Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes

Diabetes is associated with a deficit of circulating endothelial progenitor cells (EPCs), which has been attributed to their defective mobilization from the bone marrow. The basis for this mobilization defect is not completely understood, and we sought to determine if hyperglycemic conditions enhanc...

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Detalles Bibliográficos
Autores principales: Abplanalp, Wesley T., Conklin, Daniel J., Cantor, Joseph M., Ginsberg, Mark H., Wysoczynski, Marcin, Bhatnagar, Aruni, O’Toole, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079633/
https://www.ncbi.nlm.nih.gov/pubmed/27495221
http://dx.doi.org/10.2337/db16-0634