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Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity

Mitochondria are the nexus of energy metabolism, and consequently their dysfunction has been implicated in the development of metabolic complications and progression to insulin resistance and type 2 diabetes. The unique tetra-acyl phospholipid cardiolipin (CL) is located in the inner mitochondrial m...

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Detalles Bibliográficos
Autores principales: Cole, Laura K., Mejia, Edgard M., Vandel, Marilyne, Sparagna, Genevieve C., Claypool, Steven M., Dyck-Chan, Laura, Klein, Julianne, Hatch, Grant M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079636/
https://www.ncbi.nlm.nih.gov/pubmed/27495222
http://dx.doi.org/10.2337/db16-0114