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Upregulation of Mitochondrial Content in Cytochrome c Oxidase Deficient Fibroblasts

Cytochrome-c-oxidase (COX) deficiency is a frequent cause of mitochondrial disease and is associated with a wide spectrum of clinical phenotypes. We studied mitochondrial function and biogenesis in fibroblasts derived from the Cohen (CDs) rat, an animal model of COX deficiency. COX activity in CDs-f...

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Detalles Bibliográficos
Autores principales: Kogot-Levin, Aviram, Saada, Ann, Leibowitz, Gil, Soiferman, Devorah, Douiev, Liza, Raz, Itamar, Weksler-Zangen, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079646/
https://www.ncbi.nlm.nih.gov/pubmed/27780242
http://dx.doi.org/10.1371/journal.pone.0165417