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Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes

Autophagy is a highly coordinated process that is controlled at several levels including transcriptional regulation. Here, we identify the transcription factor NFE2L2/NRF2 (nuclear factor, erythroid 2 like 2) as a regulator of autophagy gene expression and its relevance in a mouse model of Alzheimer...

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Detalles Bibliográficos
Autores principales: Pajares, Marta, Jiménez-Moreno, Natalia, García-Yagüe, Ángel J., Escoll, Maribel, de Ceballos, María L., Van Leuven, Fred, Rábano, Alberto, Yamamoto, Masayuki, Rojo, Ana I., Cuadrado, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079676/
https://www.ncbi.nlm.nih.gov/pubmed/27427974
http://dx.doi.org/10.1080/15548627.2016.1208889