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Cellular minichromosome maintenance complex component 5 (MCM5) is incorporated into HIV-1 virions and modulates viral replication in the newly infected cells

The post-entry events of HIV-1 infection occur within reverse transcription complexes derived from the viral cores entering the target cell. HIV-1 cores contain host proteins incorporated from virus-producing cells. In this report, we show that MCM5, a subunit of the hexameric minichromosome mainten...

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Detalles Bibliográficos
Autores principales: Santos, Steven, Obukhov, Yuri, Nekhai, Sergei, Pushkarsky, Tatiana, Brichacek, Beda, Bukrinsky, Michael, Iordanskiy, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079758/
https://www.ncbi.nlm.nih.gov/pubmed/27414250
http://dx.doi.org/10.1016/j.virol.2016.06.023