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Validity of Quinpirole Sensitization Rat Model of OCD: Linking Evidence from Animal and Clinical Studies

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder with 1–3% prevalence. OCD is characterized by recurrent thoughts (obsessions) and repetitive behaviors (compulsions). The pathophysiology of OCD remains unclear, stressing the importance of pre-clinical studies. The aim of this artic...

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Detalles Bibliográficos
Autores principales: Stuchlik, Ales, Radostová, Dominika, Hatalova, Hana, Vales, Karel, Nekovarova, Tereza, Koprivova, Jana, Svoboda, Jan, Horacek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080285/
https://www.ncbi.nlm.nih.gov/pubmed/27833539
http://dx.doi.org/10.3389/fnbeh.2016.00209