Cargando…

Validity of Quinpirole Sensitization Rat Model of OCD: Linking Evidence from Animal and Clinical Studies

Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder with 1–3% prevalence. OCD is characterized by recurrent thoughts (obsessions) and repetitive behaviors (compulsions). The pathophysiology of OCD remains unclear, stressing the importance of pre-clinical studies. The aim of this artic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stuchlik, Ales, Radostová, Dominika, Hatalova, Hana, Vales, Karel, Nekovarova, Tereza, Koprivova, Jana, Svoboda, Jan, Horacek, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080285/ https://www.ncbi.nlm.nih.gov/pubmed/27833539 http://dx.doi.org/10.3389/fnbeh.2016.00209

Ejemplares similares

Spatial Reversal Learning in Chronically Sensitized Rats and in Undrugged Sensitized Rats with Dopamine D2-Like Receptor Agonist Quinpirole
por: Hatalova, Hana, et al.
Publicado: (2014)

Plasticity-Related Activity in the Hippocampus, Anterior Cingulate, Orbitofrontal, and Prefrontal Cortex Following a Repeated Treatment with D(2)/D(3) Agonist Quinpirole
por: Brozka, Hana, et al.
Publicado: (2021)

Pregnanolone Glutamate, a Novel Use-Dependent NMDA Receptor Inhibitor, Exerts Antidepressant-Like Properties in Animal Models
por: Holubova, Kristina, et al.
Publicado: (2014)

Common mechanisms of pain and depression: are antidepressants also analgesics?
por: Nekovarova, Tereza, et al.
Publicado: (2014)

Compulsive checking behavior of quinpirole-sensitized rats as an animal model of Obsessive-Compulsive Disorder(OCD): form and control
por: Szechtman, Henry, et al.
Publicado: (2001)

Neuroreceptor kinetics in rats repeatedly exposed to quinpirole as a model for OCD
por: Servaes, Stijn, et al.
Publicado: (2019)

Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits
por: Uttl, Libor, et al.
Publicado: (2018)

Corrigendum: Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits
por: Uttl, Libor, et al.
Publicado: (2018)

Incidental temporal binding in rats: A novel behavioral task
por: Radostova, Dominika, et al.
Publicado: (2023)

Modulation of quinpirole-induced compulsive-like behavior in rats by environmental changes: Implications for OCD rituals and for exploration and navigation
por: Zadicario, Pazit, et al.
Publicado: (2007)

Bridging disparate symptoms of schizophrenia: a triple network dysfunction theory
por: Nekovarova, Tereza, et al.
Publicado: (2014)

MK-801 Impairs Cognitive Coordination on a Rotating Arena (Carousel) and Contextual Specificity of Hippocampal Immediate-Early Gene Expression in a Rat Model of Psychosis
por: Kubík, Štěpán, et al.
Publicado: (2014)

The Effect of Psilocin on Memory Acquisition, Retrieval, and Consolidation in the Rat
por: Rambousek, Lukas, et al.
Publicado: (2014)

Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena
por: Svoboda, Jan, et al.
Publicado: (2015)

Corrigendum: Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena
por: Svoboda, Jan, et al.
Publicado: (2015)

Inter-individual differences in laboratory rats as revealed by three behavioural tasks
por: Rudolfová, Veronika, et al.
Publicado: (2022)

A virtual reality task based on animal research – spatial learning and memory in patients after the first episode of schizophrenia
por: Fajnerová, Iveta, et al.
Publicado: (2014)

A Rat Model of Alzheimer’s Disease Based on Abeta(42) and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems
por: Petrasek, Tomas, et al.
Publicado: (2016)

The dopamine D2/D3 receptor agonist quinpirole increases checking-like behaviour in an operant observing response task with uncertain reinforcement: A novel possible model of OCD()
por: Eagle, Dawn M., et al.
Publicado: (2014)

The Role of Zebrafish and Laboratory Rodents in Schizophrenia Research
por: Langova, Veronika, et al.
Publicado: (2020)

Validation of the Human–Animal Interaction Scale (HAIS) in Czech Language
por: Machová, Kristýna, et al.
Publicado: (2020)

The neurobiological link between OCD and ADHD
por: Brem, Silvia, et al.
Publicado: (2014)

Could Prolonged Usage of GPS Navigation Implemented in Augmented Reality Smart Glasses Affect Hippocampal Functional Connectivity?
por: Fajnerová, Iveta, et al.
Publicado: (2018)

Drugs Interfering with Muscarinic Acetylcholine Receptors and Their Effects on Place Navigation
por: Svoboda, Jan, et al.
Publicado: (2017)

Schizophrenia, the gut microbiota, and new opportunities from optogenetic manipulations of the gut-brain axis
por: Patrono, Enrico, et al.
Publicado: (2021)

Transient Inactivation of the Medial Prefrontal Cortex and Ventral Hippocampus Impairs Active Place Avoidance Retrieval on a Rotating Arena
por: Cernotova, Daniela, et al.
Publicado: (2021)

Fusiform Activity Distinguishes Between Subjects With Low and High Xenophobic Attitudes Toward Refugees
por: Kesner, Ladislav, et al.
Publicado: (2020)

Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task
por: Janikova, Martina, et al.
Publicado: (2021)

Application of quinpirole in the paraventricular thalamus facilitates emergence from isoflurane anesthesia in mice
por: Ao, Yawen, et al.
Publicado: (2020)

OCDE
por: Organisation for Economic Cooperation and Development. Paris
Publicado: (1994)

Mechanisms of Kappa Opioid Receptor Potentiation of Dopamine D2 Receptor Function in Quinpirole-Induced Locomotor Sensitization in Rats
por: Escobar, Angélica P, et al.
Publicado: (2017)

Functional Connectivity Changes in Obsessive–Compulsive Disorder Correspond to Interference Control and Obsessions Severity
por: Fajnerova, Iveta, et al.
Publicado: (2020)

N-Methyl-d-Aspartate Receptor – Nitric Oxide Synthase Pathway in the Cortex of Nogo-A-Deficient Rats in Relation to Brain Laterality and Schizophrenia
por: Krištofiková, Zdena, et al.
Publicado: (2013)

The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity
por: Petrasek, Tomas, et al.
Publicado: (2018)

Effect of curcumin on quinpirole induced compulsive checking: An approach to determine the predictive and construct validity of the model
por: Chimakurthy, Jithendra, et al.
Publicado: (2010)

Inside OCD: Perspectives on the Value of Storytelling with Individuals with OCD and Family Members
por: Pufahl, Jeffrey, et al.
Publicado: (2021)

Dimensions Of OCD, Feelings of Shame, Guilt and Emotion Regulation in Persons With OCD
por: Kumar, Gyanendra, et al.
Publicado: (2022)

Study of the surface properties of ZnO nanocolumns used for thin-film solar cells
por: Neykova, Neda, et al.
Publicado: (2017)

An Adenosine A(2A) Receptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis
por: Asaoka, Nozomi, et al.
Publicado: (2019)

Consequences of early postnatal benzodiazepines exposure in rats. I. Cognitive-like behavior
por: Mikulecká, Anna, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1u9bebmi0bnugr4o42nr2ftph9