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Estrogen Receptor β in Melanoma: From Molecular Insights to Potential Clinical Utility

Cutaneous melanoma is an aggressive tumor; its incidence has been reported to increase fast in the past decades. Melanoma is a heterogeneous tumor, with most patients harboring mutations in the BRAF or NRAS oncogenes, leading to the overactivation of the MAPK/ERK and PI3K/Akt pathways. The current t...

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Detalles Bibliográficos
Autores principales: Marzagalli, Monica, Montagnani Marelli, Marina, Casati, Lavinia, Fontana, Fabrizio, Moretti, Roberta Manuela, Limonta, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080294/
https://www.ncbi.nlm.nih.gov/pubmed/27833586
http://dx.doi.org/10.3389/fendo.2016.00140