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EPHA3 regulates the multidrug resistance of small cell lung cancer via the PI3K/BMX/STAT3 signaling pathway

Multidrug resistance (MDR) is a major obstacle to the treatment of small cell lung cancer (SCLC). EPHA3 has been revealed to be the most frequently mutated Eph receptor gene in lung cancer with abnormal expression. Growing evidence indicates that the signaling proteins of EPHA3 downstream, including...

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Detalles Bibliográficos
Autores principales: Peng, Juan, Wang, Qiongyao, Liu, Huanxin, Ye, Minting, Wu, Xiaoxia, Guo, Linlang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080350/
https://www.ncbi.nlm.nih.gov/pubmed/27101199
http://dx.doi.org/10.1007/s13277-016-5048-4