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Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase

Background: Germline knockout mice are invaluable in understanding the function of the targeted genes. Sometimes, however, unexpected phenotypes are encountered, due in part to the activation of compensatory mechanisms. Germline ablation of cardiac myosin light chain kinase (cMLCK) causes mild cardi...

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Detalles Bibliográficos
Autores principales: Islam, Yasmin F. K., Joseph, Ryan, Chowdhury, Rajib R., Anderson, Robert H., Kasahara, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080352/
https://www.ncbi.nlm.nih.gov/pubmed/27833563
http://dx.doi.org/10.3389/fphys.2016.00480