Cargando…

Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase

Background: Germline knockout mice are invaluable in understanding the function of the targeted genes. Sometimes, however, unexpected phenotypes are encountered, due in part to the activation of compensatory mechanisms. Germline ablation of cardiac myosin light chain kinase (cMLCK) causes mild cardi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Islam, Yasmin F. K., Joseph, Ryan, Chowdhury, Rajib R., Anderson, Robert H., Kasahara, Hideko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080352/ https://www.ncbi.nlm.nih.gov/pubmed/27833563 http://dx.doi.org/10.3389/fphys.2016.00480

Ejemplares similares

The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts
por: Chang, Audrey N., et al.
Publicado: (2013)

Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
por: Sevrieva, Ivanka R., et al.
Publicado: (2020)

p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle
por: Kalra, Jaspreet, et al.
Publicado: (2023)

Remodeling of the heart in hypertrophy in animal models with myosin essential light chain mutations
por: Kazmierczak, Katarzyna, et al.
Publicado: (2014)

Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
por: Hitsumoto, Tatsuro, et al.
Publicado: (2023)

Regulation of Myosin Light-Chain Phosphatase Activity to Generate Airway Smooth Muscle Hypercontractility
por: Álvarez-Santos, Mayra D., et al.
Publicado: (2020)

Myosin light chain kinase and myosin light chain phosphatase from Dictyostelium: effects of reversible phosphorylation on myosin structure and function
Publicado: (1987)

Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation
por: Mamidi, Ranganath, et al.
Publicado: (2014)

Distinct Roles of Smooth Muscle and Non-muscle Myosin Light Chain-Mediated Smooth Muscle Contraction
por: Sun, Jie, et al.
Publicado: (2020)

Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain
por: Gollapudi, Sampath K., et al.
Publicado: (2016)

Impact of cardiac myosin light chain kinase gene mutation on development of dilated cardiomyopathy
por: Hodatsu, Akihiko, et al.
Publicado: (2019)

New Isoform of Cardiac Myosin Light Chain Kinase and the Role of Cardiac Myosin Phosphorylation in α(1)-Adrenoceptor Mediated Inotropic Response
por: Taniguchi, Masaya, et al.
Publicado: (2015)

Dynamic Regulation of Myosin Light Chain Phosphorylation by Rho-kinase
por: Kaneko-Kawano, Takako, et al.
Publicado: (2012)

Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac muscle
por: Kampourakis, Thomas, et al.
Publicado: (2015)

The Regulation of Intestinal Mucosal Barrier by Myosin Light Chain Kinase/Rho Kinases
por: Jin, Younggeon, et al.
Publicado: (2020)

Loss of cardiac myosin light chain kinase contributes to contractile dysfunction in right ventricular pressure overload
por: Prasad, Vidhya, et al.
Publicado: (2022)

Association of myosin light chain kinase with lymphocyte membrane- cytoskeleton complex
Publicado: (1982)

The Effect of Myosin Light Chain Kinase on the Occurrence and Development of Intracranial Aneurysm
por: Song, Yaying, et al.
Publicado: (2018)

Ardipusilloside-I stimulates gastrointestinal motility and phosphorylation of smooth muscle myosin by myosin light chain kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Modulating Beta-Cardiac Myosin Function at the Molecular and Tissue Levels
por: Tang, Wanjian, et al.
Publicado: (2017)

Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle
por: Hong, Feng, et al.
Publicado: (2015)

Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis
por: Taneja, Nilay, et al.
Publicado: (2021)

Discovery of the first unconventional myosin: Acanthamoeba myosin-I
por: Pollard, Thomas D., et al.
Publicado: (2023)

Effects of phosphorylation by myosin light chain kinase on the structure of Limulus thick filaments
Publicado: (1991)

Localization and Activity of Myosin Light Chain Kinase Isoforms during the Cell Cycle
por: Poperechnaya, Angela, et al.
Publicado: (2000)

Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory Diseases
por: Xiong, Yongjian, et al.
Publicado: (2017)

Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment
por: Cao, Feng, et al.
Publicado: (2020)

Myosin Light Chain Kinase Modulates to Improve Myocardial Hypoxia/Reoxygenation Injury
por: Zhang, Qibo, et al.
Publicado: (2022)

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase
por: Lou, Sunny S., et al.
Publicado: (2015)

Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
por: Murray, Ailish, et al.
Publicado: (2010)

Maturation of Cardiac Energy Metabolism During Perinatal Development
por: Piquereau, Jérôme, et al.
Publicado: (2018)

Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function
por: Dudek, Steven M., et al.
Publicado: (2010)

Cardiac Myosin Binding Protein-C Phosphorylation Modulates Myofilament Length-Dependent Activation
por: Mamidi, Ranganath, et al.
Publicado: (2016)

Myosin Light Chain Kinase Mediates Intestinal Barrier Disruption following Burn Injury
por: Chen, Chuanli, et al.
Publicado: (2012)

Myosin Light-Chain Kinase Is Necessary for Membrane Homeostasis in Cochlear Inner Hair Cells
por: Zhu, Guang-Jie, et al.
Publicado: (2012)

Berberine Depresses Contraction of Smooth Muscle via Inhibiting Myosin Light-chain Kinase
por: Xu, Zhili, et al.
Publicado: (2017)

Contributions of Myosin Light Chain Kinase to Regulation of Epithelial Paracellular Permeability and Mucosal Homeostasis
por: He, Wei-Qi, et al.
Publicado: (2020)

NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart
por: Müller, Marion, et al.
Publicado: (2022)

Involvement of atypical protein kinase C in the regulation of cardiac glucose and long-chain fatty acid uptake
por: Habets, Daphna D. J., et al.
Publicado: (2012)

Rho Kinase's Role in Myosin Recruitment to the Equatorial Cortex of Mitotic Drosophila S2 Cells Is for Myosin Regulatory Light Chain Phosphorylation
por: Dean, Sara O., et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_p1nbrn4bcu9sf4jmthubiuggpu