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Autophagy Induced during Pancreatitis Promotes KRAS-Dependent Transformation in the Pancreas

Pancreatitis is an inflammatory disease that both facilitates and accelerates the transformation of pancreatic cells upon activation of the KRAS oncogene. Autophagy is proposed to be one of the cellular mechanisms contributing to pancreatic carcinogenesis, especially during initial stages in which t...

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Detalles Bibliográficos
Autor principal: Iovanna, Juan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080356/
https://www.ncbi.nlm.nih.gov/pubmed/27833900
http://dx.doi.org/10.3389/fonc.2016.00226