Association of morphine-induced analgesic tolerance with changes in gene expression of GluN1 and MOR1 in rat spinal cord and midbrain

OBJECTIVE(S): We aimed to examine association of gene expression of MOR1 and GluN1 at mRNA level in the lumbosacral cord and midbrain with morphine tolerance in male Wistar rats. MATERIALS AND METHODS: Analgesic effects of morphine administrated intraperitoneally at doses of 0.1, 1, 5 and 10 mg/kg w...

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Detalles Bibliográficos
Autores principales: Ahmadi, Shamseddin, Miraki, Fatemeh, Rostamzadeh, Jalal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080421/
https://www.ncbi.nlm.nih.gov/pubmed/27803778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080421/
https://www.ncbi.nlm.nih.gov/pubmed/27803778

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