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Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy
Haematopoietic stem cell (HSC) gene therapy has demonstrated potential to treat many diseases. However, current state of the art requires sophisticated ex vivo gene transfer in a dedicated Good Manufacturing Practices facility, limiting availability. An automated process would improve the availabili...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080442/ https://www.ncbi.nlm.nih.gov/pubmed/27762266 http://dx.doi.org/10.1038/ncomms13173 |