Structural characterization of twisted gastrulation provides insights into opposing functions on the BMP signalling pathway

Twisted gastrulation (Tsg) and chordin are secreted glycoproteins that function together as BMP (bone morphogenetic protein) antagonists to regulate BMP growth factor signalling. Chordin binds to BMPs, preventing them from interacting with their receptors and Tsg is known to strengthen this inhibito...

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Detalles Bibliográficos
Autores principales: Troilo, Helen, Barrett, Anne L., Zuk, Alexandra V., Lockhart-Cairns, Michael P., Wohl, Alexander P., Bayley, Christopher P., Dajani, Rana, Tunnicliffe, Richard B., Green, Lewis, Jowitt, Thomas A., Sengle, Gerhard, Baldock, Clair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080453/
https://www.ncbi.nlm.nih.gov/pubmed/26829466
http://dx.doi.org/10.1016/j.matbio.2016.01.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080453/
https://www.ncbi.nlm.nih.gov/pubmed/26829466
http://dx.doi.org/10.1016/j.matbio.2016.01.019

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