Membrane potentials regulating GPCRs: insights from experiments and molecular dynamics simulations

G-protein coupled receptors (GPCRs) form the largest class of membrane proteins in humans and the targets of most present drugs. Membrane potential is one of the defining characteristics of living cells. Recent work has shown that the membrane voltage, and changes thereof, modulates signal transduct...

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Detalles Bibliográficos
Autores principales: Vickery, Owen N, Machtens, Jan-Philipp, Zachariae, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080454/
https://www.ncbi.nlm.nih.gov/pubmed/27474871
http://dx.doi.org/10.1016/j.coph.2016.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080454/
https://www.ncbi.nlm.nih.gov/pubmed/27474871
http://dx.doi.org/10.1016/j.coph.2016.06.011

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