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Membrane potentials regulating GPCRs: insights from experiments and molecular dynamics simulations
G-protein coupled receptors (GPCRs) form the largest class of membrane proteins in humans and the targets of most present drugs. Membrane potential is one of the defining characteristics of living cells. Recent work has shown that the membrane voltage, and changes thereof, modulates signal transduct...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080454/ https://www.ncbi.nlm.nih.gov/pubmed/27474871 http://dx.doi.org/10.1016/j.coph.2016.06.011 |