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Problems and Solutions in Click Chemistry Applied to Drug Probes

Small-molecule fluorescent probes have been widely used in target identification, but this method has many disadvantages. For example, the identified proteins are usually complex, and additional biochemical studies are needed to distinguish real targets from interference results. To address this pro...

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Detalles Bibliográficos
Autores principales: Zhong, Weilong, Sun, Bo, Lu, Cheng, Yu, Hengheng, Wang, Changhua, He, Lingfei, Gu, Ju, Chen, Shuang, Liu, Yanrong, Jing, Xiangyan, Bi, Zhun, Yang, Guang, Zhou, Honggang, Sun, Tao, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080546/
https://www.ncbi.nlm.nih.gov/pubmed/27782133
http://dx.doi.org/10.1038/srep35579