Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae

The mechanism of action of valproate (VPA), a widely prescribed short chain fatty acid with anticonvulsant and anticancer properties, remains poorly understood. Here, the yeast Saccharomyces cerevisiae was used as model to investigate the biological consequences of VPA exposure. We found that low pH...

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Detalles Bibliográficos
Autores principales: Desfossés-Baron, Kristelle, Hammond-Martel, Ian, Simoneau, Antoine, Sellam, Adnane, Roberts, Stephen, Wurtele, Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080547/
https://www.ncbi.nlm.nih.gov/pubmed/27782169
http://dx.doi.org/10.1038/srep36013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080547/
https://www.ncbi.nlm.nih.gov/pubmed/27782169
http://dx.doi.org/10.1038/srep36013

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