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Functional kinomics establishes a critical node of volume-sensitive cation-Cl(−) cotransporter regulation in the mammalian brain

Cell volume homeostasis requires the dynamically regulated transport of ions across the plasmalemma. While the ensemble of ion transport proteins involved in cell volume regulation is well established, the molecular coordinators of their activities remain poorly characterized. We utilized a function...

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Detalles Bibliográficos
Autores principales: Zhang, Jinwei, Gao, Geng, Begum, Gulnaz, Wang, Jinhua, Khanna, Arjun R., Shmukler, Boris E., Daubner, Gerrit M., de los Heros, Paola, Davies, Paul, Varghese, Joby, Bhuiyan, Mohammad Iqbal H., Duan, Jinjing, Zhang, Jin, Duran, Daniel, Alper, Seth L., Sun, Dandan, Elledge, Stephen J., Alessi, Dario R., Kahle, Kristopher T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080614/
https://www.ncbi.nlm.nih.gov/pubmed/27782176
http://dx.doi.org/10.1038/srep35986