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Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein

The structural integrity of meningococcal native, micro-fluidized and activated capsular polysaccharides and their glycoconjugates – in the form most relevant to their potential use as vaccines (dilute solution) - have been investigated with respect to their homogeneity, conformation and flexibility...

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Detalles Bibliográficos
Autores principales: Abdelhameed, Ali Saber, Morris, Gordon A., Almutairi, Fahad, Adams, Gary G., Duvivier, Pierre, Conrath, Karel, Harding, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080625/
https://www.ncbi.nlm.nih.gov/pubmed/27782149
http://dx.doi.org/10.1038/srep35588