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β-Arrestin 1’s Interaction with TC45 Attenuates Stat signaling by dephosphorylating Stat to inhibit antimicrobial peptide expression

Impaired phosphatase activity leads to the persistent activation of signal transducers and activators of transcription (Stat). In mammals, Stat family members are often phosphorylated or dephosphorylated by the same enzymes. To date, only one Stat similar to mammalian Stat5a/b has been found in crus...

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Detalles Bibliográficos
Autores principales: Sun, Jie-Jie, Yang, Hui-Ting, Niu, Guo-Juan, Feng, Xiao-Wu, Lan, Jiang-Feng, Zhao, Xiao-Fan, Wang, Jin-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080627/
https://www.ncbi.nlm.nih.gov/pubmed/27782165
http://dx.doi.org/10.1038/srep35808