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β-Arrestin 1’s Interaction with TC45 Attenuates Stat signaling by dephosphorylating Stat to inhibit antimicrobial peptide expression
Impaired phosphatase activity leads to the persistent activation of signal transducers and activators of transcription (Stat). In mammals, Stat family members are often phosphorylated or dephosphorylated by the same enzymes. To date, only one Stat similar to mammalian Stat5a/b has been found in crus...
Autores principales: | Sun, Jie-Jie, Yang, Hui-Ting, Niu, Guo-Juan, Feng, Xiao-Wu, Lan, Jiang-Feng, Zhao, Xiao-Fan, Wang, Jin-Xing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080627/ https://www.ncbi.nlm.nih.gov/pubmed/27782165 http://dx.doi.org/10.1038/srep35808 |
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