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Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model

The aim of this tutorial is to introduce the fundamental concepts of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling with a special focus on their practical implementation in a typical PBPK model building workflow. To illustrate basic steps in PBPK model building, a PBPK mod...

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Detalles Bibliográficos
Autores principales: Kuepfer, L, Niederalt, C, Wendl, T, Schlender, J‐F, Willmann, S, Lippert, J, Block, M, Eissing, T, Teutonico, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080648/
https://www.ncbi.nlm.nih.gov/pubmed/27653238
http://dx.doi.org/10.1002/psp4.12134