Population Pharmacokinetic and Pharmacodynamic Modeling Analysis of GCC‐4401C, a Novel Direct Factor Xa Inhibitor, in Healthy Volunteers

GCC‐4401C, an orally active direct factor Xa inhibitor that is similar to rivaroxaban, is currently under development for venous thromboembolic disease (VTE). The purpose of this study was to characterize the pharmacokinetics (PKs) and pharmacodynamics (PDs) of GCC‐4401C by population modeling analy...

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Detalles Bibliográficos
Autores principales: Choi, HY, Choi, S, Kim, YH, Lim, HS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080649/
https://www.ncbi.nlm.nih.gov/pubmed/27511836
http://dx.doi.org/10.1002/psp4.12103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080649/
https://www.ncbi.nlm.nih.gov/pubmed/27511836
http://dx.doi.org/10.1002/psp4.12103

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