Quantitative Systems Pharmacology Model to Predict the Effects of Commonly Used Anticoagulants on the Human Coagulation Network

Warfarin is the anticoagulant of choice for venous thromboembolism (VTE) treatment, although its suppression of the endogenous clot‐dissolution complex APC:PS may ultimately lead to longer time‐to‐clot dissolution profiles, resulting in increased risk of re‐thrombosis. This detrimental effect might...

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Detalles Bibliográficos
Autores principales: Hartmann, S, Biliouris, K, Lesko, LJ, Nowak‐Göttl, U, Trame, MN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080651/
https://www.ncbi.nlm.nih.gov/pubmed/27647667
http://dx.doi.org/10.1002/psp4.12111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080651/
https://www.ncbi.nlm.nih.gov/pubmed/27647667
http://dx.doi.org/10.1002/psp4.12111

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