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Co-activator candidate interactions for orphan nuclear receptor NR2E1

BACKGROUND: NR2E1 (Tlx) is an orphan nuclear receptor that regulates the maintenance and self-renewal of neural stem cells, and promotes tumourigenesis. Nr2e1-null mice exhibit reduced cortical and limbic structures and pronounced retinal dystrophy. NR2E1 functions mainly as a repressor of gene tran...

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Detalles Bibliográficos
Autores principales: Corso-Díaz, Ximena, de Leeuw, Charles N., Alonso, Vivian, Melchers, Diana, Wong, Bibiana K. Y., Houtman, René, Simpson, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080790/
https://www.ncbi.nlm.nih.gov/pubmed/27782803
http://dx.doi.org/10.1186/s12864-016-3173-5