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Epigenetic regulation of APC in the molecular pathogenesis of gallbladder cancer

BACKGROUND & OBJECTIVES: Loss of function of adenomatous polyposis coli (APC) has been reported in cancer. The two promoters of APC, 1A and 1B also have roles in cancer. But, the epigenetic role of APC promoters is not yet clear in gallbladder cancer (GBC) and gallstone diseases (GSD). We undert...

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Detalles Bibliográficos
Autores principales: Tekcham, Dinesh Singh, Poojary, Satish S., Bhunia, Shushruta, Barbhuiya, Mustafa Ahmed, Gupta, Sanjeev, Shrivastav, Braj Raj, Tiwari, Pramod Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080933/
https://www.ncbi.nlm.nih.gov/pubmed/27748282
http://dx.doi.org/10.4103/0971-5916.191792