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No effect of PCSK9 inhibitor alirocumab on the incidence of diabetes in a pooled analysis from 10 ODYSSEY Phase 3 studies

AIMS: Statins have modest adverse effects on glycaemic control. Alirocumab, a proprotein convertase subtilisin/kexin type 9 inhibitor, lowers low-density lipoprotein cholesterol. This study assessed the effects of alirocumab on new-onset diabetes and pre-diabetes incidence in individuals without dia...

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Detalles Bibliográficos
Autores principales: Colhoun, Helen M., Ginsberg, Henry N., Robinson, Jennifer G., Leiter, Lawrence A., Müller-Wieland, Dirk, Henry, Robert R., Cariou, Bertrand, Baccara-Dinet, Marie T., Pordy, Robert, Merlet, Laurence, Eckel, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081037/
https://www.ncbi.nlm.nih.gov/pubmed/27460890
http://dx.doi.org/10.1093/eurheartj/ehw292