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HLA class II sequence variants influence tuberculosis risk in populations of European ancestry

Mycobacterium tuberculosis (M. tuberculosis) infections cause 9.0 million new tuberculosis (TB) cases and 1.5 million deaths annually1. To search for sequence variants that confer risk of TB we tested 28.3 million variants identified through whole-genome sequencing of 2,636 Icelanders for associatio...

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Detalles Bibliográficos
Autores principales: Sveinbjornsson, Gardar, Gudbjartsson, Daniel F., Halldorsson, Bjarni V., Kristinsson, Karl G., Gottfredsson, Magnus, Barrett, Jeffrey C., Gudmundsson, Larus J., Blondal, Kai, Gylfason, Arnaldur, Gudjonsson, Sigurjon Axel, Helgadottir, Hafdis T., Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Karason, Ari, Kardum, Ljiljana Bulat, Knežević, Jelena, Kristjansson, Helgi, Kristjansson, Mar, Love, Arthur, Luo, Yang, Magnusson, Olafur T., Sulem, Patrick, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Dembic, Zlatko, Nejentsev, Sergey, Blondal, Thorsteinn, Jonsdottir, Ingileif, Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081101/
https://www.ncbi.nlm.nih.gov/pubmed/26829749
http://dx.doi.org/10.1038/ng.3498