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MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat

Voltage-gated sodium channels, which are involved in pain pathways, have emerged as major targets for therapeutic intervention in pain disorders. Nav1.7, the tetrodotoxin-sensitive voltage-gated sodium channel isoform encoded by SCN9A and predominantly expressed in pain-sensing neurons in the dorsal...

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Detalles Bibliográficos
Autores principales: Shao, Jinping, Cao, Jing, Wang, Jiannan, Ren, Xiuhua, Su, Songxue, Li, Ming, Li, Zhihua, Zhao, Qingzan, Zang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081156/
https://www.ncbi.nlm.nih.gov/pubmed/27765894
http://dx.doi.org/10.1177/1744806916671523