Cargando…

MicroRNA-30b regulates expression of the sodium channel Nav1.7 in nerve injury-induced neuropathic pain in the rat

Voltage-gated sodium channels, which are involved in pain pathways, have emerged as major targets for therapeutic intervention in pain disorders. Nav1.7, the tetrodotoxin-sensitive voltage-gated sodium channel isoform encoded by SCN9A and predominantly expressed in pain-sensing neurons in the dorsal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Jinping, Cao, Jing, Wang, Jiannan, Ren, Xiuhua, Su, Songxue, Li, Ming, Li, Zhihua, Zhao, Qingzan, Zang, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081156/ https://www.ncbi.nlm.nih.gov/pubmed/27765894 http://dx.doi.org/10.1177/1744806916671523

Ejemplares similares

MiR-30b Attenuates Neuropathic Pain by Regulating Voltage-Gated Sodium Channel Nav1.3 in Rats
por: Su, Songxue, et al.
Publicado: (2017)

MicroRNA-182 Alleviates Neuropathic Pain by Regulating Nav1.7 Following Spared Nerve Injury in Rats
por: Cai, Weihua, et al.
Publicado: (2018)

Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas
por: Bird, Emma V, et al.
Publicado: (2013)

Intrathecal injection of fluorocitric acid inhibits the activation of glial cells causing reduced mirror pain in rats
por: Cao, Jing, et al.
Publicado: (2014)

Compound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgia
por: Samuels, Mark E, et al.
Publicado: (2008)

shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury
por: Cai, Weihua, et al.
Publicado: (2016)

Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7
por: Han, Chongyang, et al.
Publicado: (2007)

Sodium channel Nav1.7 in vascular myocytes, endothelium, and innervating axons in human skin
por: Rice, Frank L, et al.
Publicado: (2015)

Network topology of NaV1.7 mutations in sodium channel-related painful disorders
por: Kapetis, Dimos, et al.
Publicado: (2017)

General mechanism of spider toxin family I acting on sodium channel Nav1.7
por: Yuan, Fu-Chu, et al.
Publicado: (2022)

Identification of Navβ1 Residues Involved in the Modulation of the Sodium Channel Nav1.4
por: Islas, Angel A., et al.
Publicado: (2013)

Effects of acidosis on neuronal voltage-gated sodium channels: Nav1.1 and Nav1.3
por: Ghovanloo, Mohammad-Reza, et al.
Publicado: (2018)

Phylogenetic relationships of the supercontig of sodium channel subunit I (NaV) in 17 species of Anopheles (Diptera: Culicidae)
por: Santos, Valéria Silva, et al.
Publicado: (2022)

Na(v)1.7 protein and mRNA expression in the dorsal root ganglia of rats with chronic neuropathic pain★
por: Liu, Chao, et al.
Publicado: (2012)

Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity
por: Kerth, Clara M., et al.
Publicado: (2020)

Gene Transcript Alterations in the Spinal Cord, Anterior Cingulate Cortex, and Amygdala in Mice Following Peripheral Nerve Injury
por: Su, Songxue, et al.
Publicado: (2021)

Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels
por: Xie, Man-Xiu, et al.
Publicado: (2018)

Computational pipeline to probe NaV1.7 gain-of-function variants in neuropathic painful syndromes
por: Toffano, Alberto A., et al.
Publicado: (2020)

Novel Mutations Mapping to the Fourth Sodium Channel Domain of Nav1.7 Result in Variable Clinical Manifestations of Primary Erythromelalgia
por: Cregg, Roman, et al.
Publicado: (2013)

Increase of Sodium Channels (Nav 1.8 and Nav 1.9) in Rat Dorsal Root Ganglion Neurons Exposed to Autologous Nucleus Pulposus
por: Watanabe, Kazuyuki, et al.
Publicado: (2014)

Sodium channel Nav1.7 expression is upregulated in the dorsal root ganglia in a rat model of paclitaxel-induced peripheral neuropathy
por: Xiao, Yun, et al.
Publicado: (2016)

Na(+)/Ca(2+) selectivity in the bacterial voltage-gated sodium channel NavAb
por: Corry, Ben
Publicado: (2013)

Electrophysiological characterization of schizophrenia-associated variants in NaV1.2 sodium channel
por: Suslova, M., et al.
Publicado: (2022)

Inhibition of the Nav1.7 Channel in the Trigeminal Ganglion Relieves Pulpitis Inflammatory Pain
por: Kwon, Minjee, et al.
Publicado: (2021)

Influence of androgenic blockade with flutamide on pain behaviour and expression of the genes that encode the NaV1.7 and NaV1.8 voltage-dependent sodium channels in a rat model of postoperative pain
por: Barbosa Neto, José Osvaldo, et al.
Publicado: (2019)

Heterologous functional expression of ascidian Nav1 channels and close relationship with the evolutionary ancestor of vertebrate Nav channels
por: Kawai, Takafumi, et al.
Publicado: (2021)

Left-Shifted Nav Channels in Injured Bilayer: Primary Targets for Neuroprotective Nav Antagonists?
por: Morris, Catherine E., et al.
Publicado: (2012)

Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics
por: Dvorak, Nolan M., et al.
Publicado: (2020)

The Functional Role of Voltage-Gated Sodium Channel Nav1.5 in Metastatic Breast Cancer
por: Luo, Qianxuan, et al.
Publicado: (2020)

An α–π transition in S6 shapes the conformational cycle of the bacterial sodium channel NavAb
por: Choudhury, Koushik, et al.
Publicado: (2022)

Role of the voltage-gated sodium channel Nav1.6 in glioma and candidate drugs screening
por: Ai, Yong, et al.
Publicado: (2023)

CDYL suppresses epileptogenesis in mice through repression of axonal Nav1.6 sodium channel expression
por: Liu, Yongqing, et al.
Publicado: (2017)

Nav1.7 and Nav1.8: Diabetes-induced Changes in Primary Sensory Neurons in Rats
por: Lv, Jianlin, et al.
Publicado: (2016)

Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit
por: Kubota, Tomoya, et al.
Publicado: (2017)

Cutaneous nerve fiber and peripheral Nav1.7 assessment in a large cohort of patients with postherpetic neuralgia
por: Fetell, Michael, et al.
Publicado: (2023)

A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb
por: Gamal El-Din, Tamer M., et al.
Publicado: (2013)

Lidocaine reduces pain behaviors by inhibiting the expression of Nav1.7 and Nav1.8 and diminishing sympathetic sprouting in SNI rats
por: Li, Xiaoxiao, et al.
Publicado: (2022)

Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel
por: Chang, Wonseok, et al.
Publicado: (2017)

3’-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model
por: Zhang, Fan, et al.
Publicado: (2019)

Membrane protein Nav1.7 contributes to the persistent post-surgical pain regulated by p-p65 in dorsal root ganglion (DRG) of SMIR rats model
por: Li, Zhisong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_v0b33r8k5motm7qdais9kasuo9