Decreased Integrity, Content, and Increased Transcript Level of Mitochondrial DNA Are Associated with Keratoconus

Oxidative stress may play an important role in the pathogenesis of keratoconus (KC). Mitochondrial DNA (mtDNA) is involved in mitochondrial function, and the mtDNA content, integrity, and transcript level may affect the generation of reactive oxygen species (ROS) and be involved in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Hao, Xiao-Dan, Chen, Zhao-Li, Qu, Ming-Li, Zhao, Xiao-Wen, Li, Su-Xia, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081165/
https://www.ncbi.nlm.nih.gov/pubmed/27783701
http://dx.doi.org/10.1371/journal.pone.0165580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081165/
https://www.ncbi.nlm.nih.gov/pubmed/27783701
http://dx.doi.org/10.1371/journal.pone.0165580

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