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Supercoiling Effects on Short-Range DNA Looping in E. coli

DNA-protein loops can be essential for gene regulation. The Escherichia coli lactose (lac) operon is controlled by DNA-protein loops that have been studied for decades. Here we adapt this model to test the hypothesis that negative superhelical strain facilitates the formation of short-range (6–8 DNA...

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Detalles Bibliográficos
Autores principales: Mogil, Lauren S., Becker, Nicole A., Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081198/
https://www.ncbi.nlm.nih.gov/pubmed/27783696
http://dx.doi.org/10.1371/journal.pone.0165306