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Supercoiling Effects on Short-Range DNA Looping in E. coli
DNA-protein loops can be essential for gene regulation. The Escherichia coli lactose (lac) operon is controlled by DNA-protein loops that have been studied for decades. Here we adapt this model to test the hypothesis that negative superhelical strain facilitates the formation of short-range (6–8 DNA...
Autores principales: | Mogil, Lauren S., Becker, Nicole A., Maher, L. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081198/ https://www.ncbi.nlm.nih.gov/pubmed/27783696 http://dx.doi.org/10.1371/journal.pone.0165306 |
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