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Role of Sialidase in Long-Term Potentiation at Mossy Fiber-CA3 Synapses and Hippocampus-Dependent Spatial Memory
Sialic acid bound to glycans in glycolipids and glycoproteins is essential for synaptic plasticity and memory. Sialidase (EC 3.2.1.18), which has 4 isozymes including Neu1, Neu2, Neu3 and Neu4, regulates the sialylation level of glycans by removing sialic acid from sialylglycoconjugate. In the prese...
Autores principales: | Minami, Akira, Saito, Masakazu, Mamada, Shou, Ieno, Daisuke, Hikita, Tomoya, Takahashi, Tadanobu, Otsubo, Tadamune, Ikeda, Kiyoshi, Suzuki, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081204/ https://www.ncbi.nlm.nih.gov/pubmed/27783694 http://dx.doi.org/10.1371/journal.pone.0165257 |
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