The Impact of Methylenetetrahydrofolate Reductase C677T Polymorphism on Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation with Methotrexate Prophylaxis

Pharmacogenomics can explain the inter-individual differences in response to drugs, including methotrexate (MTX) used for acute graft-versus-host disease (aGVHD) prophylaxis during hematopoietic stem cell transplantation (HSCT). In real-world practice, preplanned MTX dose is arbitrarily modified acc...

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Detalles Bibliográficos
Autores principales: Byun, Ja Min, Kim, Hea-Lim, Shin, Dong-Yeop, Koh, Youngil, Yoon, Sung-Soo, Seong, Moon-Woo, Park, Sung Sup, Kim, Jin Hee, Lee, Yun-Gyoo, Kim, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081210/
https://www.ncbi.nlm.nih.gov/pubmed/27783703
http://dx.doi.org/10.1371/journal.pone.0163998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081210/
https://www.ncbi.nlm.nih.gov/pubmed/27783703
http://dx.doi.org/10.1371/journal.pone.0163998

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