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Inhibiting MicroRNA-503 and MicroRNA-181d with Losartan Ameliorates Diabetic Nephropathy in KKAy Mice

BACKGROUND: Diabetic nephropathy (DN) is the most lethal diabetic microvascular complication; it is a major cause of renal failure, and an increasingly globally prominent healthcare problem. MATERIAL/METHODS: To identify susceptible microRNAs for the pathogenesis of DN and the targets of losartan tr...

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Detalles Bibliográficos
Autores principales: Zhu, XinWang, Zhang, CongXiao, Fan, QiuLing, Liu, XiaoDan, Yang, Gang, Jiang, Yi, Wang, LiNing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081237/
https://www.ncbi.nlm.nih.gov/pubmed/27770539
http://dx.doi.org/10.12659/MSM.900938