An Empirical Prior Improves Accuracy for Bayesian Estimation of Transcription Factor Binding Site Frequencies within Gene Promoters

A Bayesian method for sampling from the distribution of matches to a precompiled transcription factor binding site (TFBS) sequence pattern (conditioned on an observed nucleotide sequence and the sequence pattern) is described. The method takes a position frequency matrix as input for a set of repres...

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Detalles Bibliográficos
Autor principal: Ramsey, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081247/
https://www.ncbi.nlm.nih.gov/pubmed/27812284
http://dx.doi.org/10.4137/BBI.S29330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081247/
https://www.ncbi.nlm.nih.gov/pubmed/27812284
http://dx.doi.org/10.4137/BBI.S29330

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