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Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells

Increasing evidence highlighted the role of cancer stem cells (CSCs) in the development of tumor resistance to therapy, particularly in glioblastoma (GBM). Therefore, the development of new therapies, specifically directed against GBM CSCs, constitutes an important research avenue. Considering the e...

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Detalles Bibliográficos
Autores principales: Angeletti, Francesca, Fossati, Gianluca, Pattarozzi, Alessandra, Würth, Roberto, Solari, Agnese, Daga, Antonio, Masiello, Irene, Barbieri, Federica, Florio, Tullio, Comincini, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081386/
https://www.ncbi.nlm.nih.gov/pubmed/27833530
http://dx.doi.org/10.3389/fnmol.2016.00107