Cargando…

A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire

Many infections are caused by pathogens that are similar, but not identical, to previously encountered viruses, bacteria, or vaccines. In such re-infections, pathogens introduce known antigens, which are recognized by memory T cells and new antigens that activate naive T cells. How preexisting memor...

Descripción completa

Detalles Bibliográficos
Autores principales: Oberle, Susanne G., Hanna-El-Daher, Layane, Chennupati, Vijaykumar, Enouz, Sarah, Scherer, Stefanie, Prlic, Martin, Zehn, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081394/
https://www.ncbi.nlm.nih.gov/pubmed/27732840
http://dx.doi.org/10.1016/j.celrep.2016.09.072