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A Minimum Epitope Overlap between Infections Strongly Narrows the Emerging T Cell Repertoire
Many infections are caused by pathogens that are similar, but not identical, to previously encountered viruses, bacteria, or vaccines. In such re-infections, pathogens introduce known antigens, which are recognized by memory T cells and new antigens that activate naive T cells. How preexisting memor...
Autores principales: | Oberle, Susanne G., Hanna-El-Daher, Layane, Chennupati, Vijaykumar, Enouz, Sarah, Scherer, Stefanie, Prlic, Martin, Zehn, Dietmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081394/ https://www.ncbi.nlm.nih.gov/pubmed/27732840 http://dx.doi.org/10.1016/j.celrep.2016.09.072 |
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