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Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat

The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The sensitization of capsaicin-sensitive TRPV1 io...

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Detalles Bibliográficos
Autores principales: Omerbašić, Damir, Smith, Ewan St. J., Moroni, Mirko, Homfeld, Johanna, Eigenbrod, Ole, Bennett, Nigel C., Reznick, Jane, Faulkes, Chris G., Selbach, Matthias, Lewin, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081396/
https://www.ncbi.nlm.nih.gov/pubmed/27732851
http://dx.doi.org/10.1016/j.celrep.2016.09.035