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Osteopontin is a key player for local adipose tissue macrophage proliferation in obesity

OBJECTIVE: Recent findings point towards an important role of local macrophage proliferation also in obesity-induced adipose tissue inflammation that underlies insulin resistance and type 2 diabetes. Osteopontin (OPN) is an inflammatory cytokine highly upregulated in adipose tissue (AT) of obese and...

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Detalles Bibliográficos
Autores principales: Tardelli, Matteo, Zeyda, Karina, Moreno-Viedma, Veronica, Wanko, Bettina, Grün, Nicole G., Staffler, Günther, Zeyda, Maximilian, Stulnig, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081407/
https://www.ncbi.nlm.nih.gov/pubmed/27818939
http://dx.doi.org/10.1016/j.molmet.2016.09.003