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High-Throughput Analysis of the T Cell Receptor Beta Chain Repertoire in PBMCs from Chronic Hepatitis B Patients with HBeAg Seroconversion

T lymphocytes are the most important immune cells that affect both the development and treatment of hepatitis B. We used high-throughput sequencing to determine the diversity in the V and J regions of the TCRβ chain in 4 chronic hepatitis B patients before and after HBeAg seroconversion. Here, we de...

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Detalles Bibliográficos
Autores principales: Qu, Yachao, Huang, Yong, Liu, Di, Huang, Yinuo, Zhang, Zhiyi, Mi, Zhiqiang, An, Xiaoping, Tong, Yigang, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081459/
https://www.ncbi.nlm.nih.gov/pubmed/27818694
http://dx.doi.org/10.1155/2016/8594107